【Solubility】Slightly soluble in water (pH 1.2-7.7), freely soluble in ethanol and acetone, soluble in ISO acetone, insoluble in heptane.。
【Melting point】118℃ -128℃
【Water content】≤0.5%
【Heavy metal】≤20ppm
【Chiral purity】RP isomer ≤ 0.15%
【Content】98.0% — 102.0%
【Storage】Shade, seal and store in a dry place.
【Chemical structural formula】
Properties
Summary
Sofibibuvir is a prodrug, which can be metabolized to 2 '- deoxy-2' - deoxy-2 '- α- Fluorine- β- C-methyluridine-5 '- monophosphate, used in the treatment of hepatitis C. Sofibvir is a direct acting antiviral drug, which inhibits HCV RNA dependent RNA polymerase, NS5B Gene. NS5B Gene is essential for HCV replication.
Manufacturing
