Esomeprazole is gradually replacing omeprazole as the first choice in the treatment of peptic ulcer, gastroesophageal reflux disease and other acid-related diseases. The pharmaceutically acceptable salts of esomeprazole include sodium, magnesium, lithium, potassium, calcium, strontium and ammonium salts, etc. AstraZeneca company believes that sodium salt and magnesium salt can make preparations with better drug performance, so it has developed esomeprazole magnesium enteric coated tablets / capsules and esomeprazole sodium lyophilized powder. Esomeprazole magnesium enteric coated tablets / capsules is more convenient, so it is favored by more patients in clinical use. Ufeprazole is esomeprazole thiamidine, also known as ufeprazole, which is mainly used for the synthesis of esomeprazole.