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Antineoplastic Agents

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CAS:165800-06-6
Molecular Formula:C5H12N2O8P2
(1-Hydroxy-2-Imidazol-1-Yl-1-Phosphonoethyl)Phosphonic Acid,Hydrate; Zoledronic Acid Monohydrate; (1-Hydroxy-2-(1H-Imidazol-1-Yl)Ethane-1,1-Diyl)Diphosphonic Acid Hydrate; 1-Hydroxy-2-(1-Imidazolyl)Ethane-1,1-Diphosphonic Acid Monohydrate
Brief Introduction
Zoledronic acid monohydrate can be an effective osteoclast inhibitor, which can induce osteoclast apoptosis by inhibiting the enzyme of methylglutaric acid pathway and preventing the isoprene of small GTP binding proteins such as Ras and Rho.
CAS:17902-23-7
Molecular Formula:C8H9FN2O3
Riol; Neberk; Exonal; Tetrahydrofuryl-5-Fluorouracil; 5-Fluoro-1-(Tetrahydrofuran-2-Yl)Pyrimidine-2,4(1H,3H)-Dione; Fulaid; Lifril; Ft-207; 5-Fluoro-1-(Tetrahydro-2-Furyl)Uracil; 5-Fluoro-1-(Tetrahydro-2-Furfuryl)Uracil; Fental; Fluaid; Lamar; Nitobanil; Nsc-148958; Phthorafur; Sinoflurol; Sunfral; 5-Fluoro-1-(Tetrahydro-2-Fuanyl)-2,4-(1H,3H)-Pyrimidinedione, Citofur, Exonal, Fental,
Brief Introduction
This product is a derivative of 5-fluorouracil, with the same function and use as 5-fluorouracil, but with low toxicity and high chemotherapy index. In vivo, it is activated by liver enzymes and converted into 5-fluorouracil to play an anticancer role. It is effective for gastric cancer, colon cancer, rectal cancer, pancreatic cancer, breast cancer and lung cancer.
CAS:183319-69-9
Molecular Formula:C22H24ClN3O4
Erlotinib-D6 Hcl; Erlotinib Hcl Salt; Erlotinib Hcl; N-(3-Ethynylphenyl)-6,7-Bis(2-Methoxyethoxy)Quinazolin-4-Amine Hydrochloride; Erlotinib,Os-774; Erlotinib (Hydrochloride)
Brief Introduction
Erotinib hydrochloride is a reversible inhibitor of small molecule epidermal growth factor receptor tyrosine kinase, which is mainly used in the second-line or third-line treatment of locally advanced or metastatic non-small cell lung cancer and the treatment of pancreatic cancer.
CAS:231277-92-2
Molecular Formula:C29H26ClFN4O4S
Lapatinib (2Tsoh); 4-{[3-Chloro-4-(3-Fluoro-Benzyloxy)-Phenyl]Amino}-6-(5-{[(2-Methansulfonyl-Ethyl)Amino]Methyl}-Furan-2-Yl)Quinazoline; N-{3-Chloro-4-[(3-Fluorobenzyl)Oxy]Phenyl}-6-[5-({[2-(Methanesulphonyl)Ethyl]Amino}Methyl)-Furan-2-Yl]-4-Quinazolinamine; N-[3-Chloro-4-[(3-Fluorophenyl)Methoxy]Phenyl]-6-[5-[(2-Methylsulfonylethylamino)Methyl]-2-Furyl]Quinazolin-4-Amine; N-{3-Chloro-4-[(3-Fluorobenzyl) Oxy]Phenyl}-6-[5-({[2-(Methanesulphonyl) Ethyl]Amino}Methyl)-2-Furyl]-4-Quinazolinamine; 4-{[3-Chloro-4-(3-Fluoro-Benzyloxy)-Phenyl]Amino}-6-(5-{[(2-Methanesulphonyl-Ethyl)Amino]Methyl}-Furan-2-Yl)Quinazoline; 4-Quinazolinamine, N-[3-Chloro-4-[(3-Fluorophenyl)Methoxy]Phenyl]-6-[5-[[[2-(Methylsulfonyl)Ethyl]Amino]Methyl]-2-Furanyl]-; Lapatinib(Tinibs); Lapatinib Base; N-[3-Chloro-4-[(3-Fluorophenyl)Methoxy]Phenyl]-6-[5-[[[2-(Methylsulfonyl)Ethyl]Amino]Methyl]-2-Furanyl]-4-Quinazolinamine; N-(3-Chloro-4-((3-Fluorobenzyl)Oxy)Phenyl)-6-(5-(((2-(Methylsulfonyl)Ethyl)Amino)Methyl)Furan-2-Yl)Quinazolin-4-Amine
Brief Introduction
Lapatinib is an oral reversible small molecule tyrosine kinase inhibitor targeting her-1/ HER-2. The biological effect of this mode of action on inhibiting the proliferation and growth of tumor cells is much greater than that of inhibiting only one of the targets. The so-called targeted therapeutic drugs refer to the drugs that target some receptors, genes or key proteins, and then targeted to kill the relevant tumor cells.
CAS:302962-49-8
Molecular Formula:C22H26ClN7O2S
Dasatinib Tablets; Sprycel; Bms-354825; Bms 354825; N-(2-Chloro-6-Methylphenyl)-2-[[6-[4-(2-Hydroxyethyl)Piperazin-1-Yl]-2-Methylpyrimidin-4-Yl]Amino]-1,3-Thiazole-5-Carboxamide
Brief Introduction
Dasatinib is a gray white to yellow solid chemical. Chemical name: n - (2-chloro-6-methylphenyl) - 2 - [[6 - [4 - (2-hydroxyethyl) - 1-piperazinyl] - 2-methyl-4-pyrimidinyl] amino] - 5-thiazolamide. Dasatinib is an antitumor drug. Clinically, it mainly treats adult patients with Philadelphia chromosome positive (Ph +) chronic myeloid leukemia (CML) in chronic phase, accelerated phase and acute phase (acute granulosis and acute lymphoblasty).
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