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CAS:1225278-16-9
Molecular Formula:C26H21F2N5O3
Alias
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DIC; N-[2,5-Difluoro-4-[[2-(1-Methyl-1H-Pyrazol-4-Yl)-4-Pyridinyl]Oxy]Phenyl]-N'-Phenyl-1,1-Cyclopropanedicarboxamide; N-[2,5-Difluoro-4-[[2-(1-Methyl-1H-Pyrazol-4-Yl)-4-Pyridinyl]Oxy]Phenyl]-N'-Phenyl-1,1-Cyclopropanedicarboxamide Dcc-2618; C-Kit-In-1; Dcc-2618, >98%; Dcc-2618?, >98%; Cs-937; Dcc2618; Dcc 2618
Brief Introduction
It has potential anti-tumor activity
CAS:1421373-66-1
Molecular Formula:C28H33N7O2.CH4O3S
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Mereletinib Mesylate; N-[2-[[2-(Dimethylamino)Ethyl]Methylamino]-4-Methoxy-5-[[4-(1-Methyl-1H-Indol-3-Yl)-2-Pyrimidinyl]Amino]Phenyl]-2-Propenamide Methanesulfonate N-[2-[2-(Dimethylamino)Ethyl-Methylamino]-4-Methoxy-5-[[4-(1-Methylindol-3-yl)Pyrimidin-2-yl]Amino]Phenyl]prop-2-Enamide;Methanesulfonic acid
Brief Introduction
Azd9291 (methanesulfonate), or oxitinib mesylate, is applicable to the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) who have been previously treated with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) or have disease progression after treatment, and who are confirmed to have positive egfrt790m mutation. Azd9291 (methanesulfonate) has high selectivity. Its IC50 for t790m/l858r mutation and exon 19 deletion EGFR are 11.4nm and 12.9nm respectively, while its IC50 for wild-type EGFR is 494nm. Oxitinib is an irreversible inhibitor of EGFR and can form covalent bonds with molecular targets. Therefore, theoretically, the response lasts longer and the chance of drug resistance is reduced accordingly.
CAS:180288-69-1
Molecular Formula:C10H14N6O5
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Herceptin; Anti HER2, Ig Gamma-1 Chain C Region; Recombinant Humanized anti-HER2 Antibody; Rhumab HER2
Brief Introduction
Trastuzumab is used to treat breast cancer. It is effective against tumors that overexpress the HER2/neu protein. As part of a chemotherapy regimen for the adjuvant treatment of node-positive, HER2/neu-positive cancers.
CAS:41575-94-4
Molecular Formula:C6H12N2O4Pt
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Paraplatin; 1,1-Cyclobutanedicarboxylatediammineplatinum(Ii); 1-Cyclobutanedicarboxylato(2-)-O,O')-Diammine((Sp-4-2)-Platinu; 1-Cyclobutanedicarboxylato)Diammine-(Cis-Platinum(Ii; Diammine(1,1-Cyclobutanedicarboxylato)Platinum(Ii); Carboplatinum; Cis-Diamine(1,1-Cyclobutanedicarboxylato)Platinum
Brief Introduction
The second generation of platinum anticancer drugs have basically the same effect and use as cisplatin. Its activity to some tumors is higher than that of cisplatin. As a radiosensitizer, it is stronger than cisplatin under hypoxia conditions. It is mainly used for ovarian cancer, testicular cancer, small cell lung cancer and head and neck cancer.
CAS:57-22-7
Molecular Formula:C46H56N4O10
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22-Oxovincaleukoblastine; Leurocristine; Vinkristin; Vincrystine; Leucristine; Vincristin; Vincristina; rel-Vincristine; Vincristinum; Tecnocris; Kyocristine; Vincristine (INN); VIN; Vincrstine; Oncotcs; (+)-Vincristine; Tecnocris (TN); LCR; VCR; Vincasar (1:1 Sulfate salt); Oncovin (1:1 Sulfate salt); Vincrex (1:1 Sulfate salt); Oncovin (Brand name); Leurocristine;NSC-67574;22-Oxovincaleukoblastine; 22-oxo-Vincaleukoblastine; Vincristine (Leurocristine); Vincaleukoblastine, 22-oxo- 22-Oxovincaleukoblastine; Methyl (1R,9R,10S,11R,12R,19R)-11-(Acetyloxy)-12-Ethyl-4-[(13S,15S,17S)-17-Ethyl-17-Hydroxy-13-(Methoxycarbonyl)-1,11-Diazatetracyclo[13.3.1.0^{4,12}.0^{5,10}]Nonadeca-4(12),5,7,9-Tetraen-13-yl]-8-Formyl-10-Hydroxy-5-Methoxy-8,16-Diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]Nonadeca-2(7),3,5,13-Tetraene-10-Carboxylate; Methyl (1R,9R,10S,11R,12R,19R)-11-Acetyloxy-12-Ethyl-4-[(13S,15S,17S)-17-Ethyl-17-Hydroxy-13-Methoxycarbonyl-1,11-Diazatetracyclo[13.3.1.04,12.05,10]Nonadeca-4(12),5,7,9-Tetraen-13-yl]-8-Formyl-10-Hydroxy-5-Methoxy-8,16-Diazapentacyclo[10.6.1.01,9.02,7.016,19]Nonadeca-2,4,6,13-Tetraene-10-Carboxylate
Brief Introduction
Natural plant anti-tumor drug, used to treat acute leukemia and malignant lymphoma, small cell lung cancer and breast cancer
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