N-(2,6-Dichlorophenyl)-4,5-Dihydro-1H-Imidazol-2-Amine; 2-(2',6'-Dichlorophenylamino)-Imidazoline; [14C]-Clonidine; [3H]-Clonidine; Catapres-Tts; Clonidine; Catarpres; Adesipress; Duraclon; Clonidin; Catarpresan; Catapressan; Catapresan; Chlornidinum

Brief Introduction

Clonidine (cataples) is a drug originally approved for the treatment of hypertension. However, because clonidine has a sedative effect, it has been found that clonidine can help people with ADHD, such as hyperactivity, impulsivity, aggression, excessive excitement and sleep difficulties.

(2R,3S)-5-[3-(Tert-Butylamino)-2-Hydroxypropoxy]-1,2,3,4-Tetrahydronaphthalene-2,3-Diol

MSDS

CAS:42200-33-9

Molecular Formula:C17H27NO4

Alias

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Nadololum [Inn-Latin]; Corgaretic; Nadolol; Solgol; (2R,3S)-5-(3-(Tert-Butylamino)-2-Hydroxypropoxy)-1,2,3,4-Tetrahydronaphthalene-2,3-Diol; Anabet; Corgard; 5-[3-[(1,1-Dimethylethyl)-Amino]-2-Hydroxypropoxy]-1,2,3,4-Tetrahydro-2,3-Cis-Naphthalenediol; 5-[3-(Tert-Butylamino)-2-Oxopropoxy]-1,2,3,4-Tetrahydronaphthalene-2,3-Diol; Nadic; [14C]-Nadolol; Nadololum; 1-Tert.-Butylamino-3-(1,2,3,4-Tetrahydro-2,3-Dihydroxy-5-Napthyloxy)-2-Propanol

Brief Introduction

Nadolol (corgard, solgol, anabet, sq11725) is a non selective β- Adrenergic receptor antagonists have antihypertensive and antiarrhythmic activities.

Oxilorphan

MSDS

CAS:42281-59-4

Molecular Formula:C20H27NO2

Alias

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3,14-Dihydroxy-N-Cyclopropylmethylmorphinan; Oxilorfano [Inn-Spanish]; (-)-17-Cyclopropylmethylmorphinan-3,4-Diol; (L)-Bc-2605; Bristol Laboratories Bc 2605; Levo-Bc-2605; Einecs 255-749-8; Unii-9Y9J2J74To; 9Y9J2J74To

Brief Introduction

Oxilorphan (INN, USAN) (developmental code name L-BC-2605) is an opioid antagonist of the morphinan family that was never marketed. It acts as a μ-opioid receptor (MOR) antagonist but a κ-opioid receptor (KOR) partial agonist, and has similar effects to naloxone and around the same potency as an MOR antagonist. Oxilorphan has some weak partial agonist actions at the MOR (with miosis, nausea, dizziness, and some euphoria observed) and can produce hallucinogenic/dissociative effects at sufficient doses, indicative of KOR activation. It was trialed for the treatment of opioid addiction, but was not developed commercially. The KOR agonist effects of oxilorphan are associated with dysphoria, which combined with its hallucinogenic effects, serve to limit its clinical usefulness; indeed, many patients who experienced these side effects refused to take additional doses in clinical trials.

Diltiazem

MSDS

CAS:42399-41-7

Molecular Formula:C22H26N2O4S

Alias

More Information

Tildiem300Lp; Diltiazen; Coras; Adizem Xl; [(2S,3S)-5-[2-(Dimethylamino)Ethyl]-2-(4-Methoxyphenyl)-4-Oxo-2,3-Dihydro-1,5-Benzothiazepin-3-Yl] Acetate; D-Cis-Diltiazem; Cardizem; Dilt-Cd

Brief Introduction

Diltiazem is a kind of antihypertensive drug used in the treatment of mild to moderate hypertension. It is one of calcium channel blockers. In addition to the treatment of mild to moderate hypertension, diltiazem is also very effective in angina pectoris and hypertrophic cardiomyopathy. Diltiazem has the effect of reducing peripheral vascular resistance by relaxing vascular smooth muscle, so as to reduce blood pressure.

Butorphanol

MSDS

CAS:42408-82-2

Molecular Formula:C21H29NO2

Alias

More Information

Levo-Bc 2627; 17-(Cyclobutylmethyl)-Morphinan-14-Diol; L-3,14-Dihydroxy-N-(Cyclobutylmethyl)Morphinan; 3,14-Dihydroxy-N-Cyclobutylmethylmorphinan; Bc 2627,(-); L-Bc 2627; Butorphanal; (-)-17-(Cyclobutylmethyl)-3,14B-Dihydroxymorphinan; N-Cyclobutylmethyl-3,14-Dihydroxymorphinan; 17-(Cyclobutylmethyl)Morphinan-3,14-Diol

Brief Introduction

Butorphanol is levorphanol in which a hydrogen at position 14 of the morphinan skeleton is substituted by hydroxy and one of the hydrogens of the N-methyl group is substituted by cyclopropyl. A semi-synthetic opioid agonist-antagonist analgesic, it is used as its (S,S)-tartaric acid salt for relief or moderate to severe pain. It has a role as an opioid analgesic, a mu-opioid receptor agonist, a kappa-opioid receptor agonist and an antitussive.

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