Pharmaceutical Raw Materials

It is used in organic synthesis, therapeutic drugs (vasodilators) and explosives.

Riociguat (trade name Adempas) is a novel drug (by Bayer) that is a stimulator of soluble guanylate cyclase (sGC). Clinical trials have looked at riociguat as a new approach to treat two forms of pulmonary hypertension (PH): chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension (PAH). Riociguat constitutes the first drug of a novel class of sGC stimulators.

The molecular formula of minaxolone is C25H43NO3.

BENZQUINAMIDE (p2647) is an antiemetic agent and can be combined with α 2A, α 2B, and α 2C adrenergic receptor（ α 2-Ar) binding, Ki values were 1365, 691 and 545 nm, respectively.

Terazosin hydrochloride is a long-term selective drug α 1 receptor blocker is a derivative of quinazoline. By reducing the smooth muscle tension at the outlet of bladder, it can relieve dysuria caused by smooth muscle tension in benign prostatic hyperplasia. Terazosin hydrochloride can reduce blood pressure and maintain normal cardiac output. It can improve the metabolic disorders of blood lipids, blood glucose, blood uric acid and male sexual dysfunction. It is suitable for the treatment of hypertension and congestive heart failure. It can also be used for prostate hypertrophy. The treatment of mild and moderate benign prostatic hyperplasia caused by frequent micturition, urgency, nocturia increase, small urine volume, acute and chronic urinary incontinence and other stimulating symptoms, at the same time, it can improve the micturition hesitation, intermittent urine line, terminal drip urine, thin and weak urine line, incomplete micturition and so on. Treatment of chronic, non bacterial prostatitis and prostatitis * can also be used for female bladder neck obstruction and colon surgery before removal of urethral catheter, which can prevent acute urinary retention.