Safotibant (INN) also known by the research code LF22-0542 is a non-peptide bradykinin B1 antagonist. It displayed binding Ki values of 0.35 and 6.5 nM at cloned human and mouse B1 receptors, respectively, while having no affinity for either human, mouse, or rat B2 receptors at concentrations up to 10 μM. This means that LF22-0542 is at least 4000 times selective for the B1 receptor over the B2 receptor. Systemic administration of LF22-0542 inhibited acute pain induced by acetic acid, formalin, and a hot plate. It also reversed acute inflammatory pain induced by carrageenan, and persistent inflammatory pain induced by CFA. In a neuropathic pain model, LF22-0542 reversed the thermal hyperalgesia, but not the mechanical hyperalgesia.

(+)-3,4-Dimethyl-2-Phenylmorpholine

MSDS

CAS:634-03-7

Molecular Formula:C12H17NO

Alias

More Information

Dimethyl-3,4-Phenyl-2-Morpholin; Phendimetrazine; 3,4-Dimethyl-2-Phenyl-Morpholine; (2S,3S)-3,4-Dimethyl-2-Phenylmorpholine; Fendimetrazina; Mephenmetrazine; Antapentan; Phendimetrazinum

Brief Introduction

Phendimetrazine is a weight loss medication. Phendimetrazine is chemically related to amphetamines and is a Schedule III drug under the Convention on Psychotropic Substances and in the US since 1970.

(2R,3S,4R,5R)-2-Fluoranyl-3,4,5,6-Tetrahydroxyhexanal

MSDS

CAS:63503-12-8

Molecular Formula:C6H11FO5

Brief Introduction

Fluorodeoxyglucose is a fluoro derivative of 2-deoxyglucose. Its complete chemical name is 2-fluoro-2-deoxy-D-glucose, usually referred to as 18F-FDG or FDG. FDG is most commonly used in medical imaging equipment of positron emission tomography (PET): Fluorine in FDG molecules is fluorine-18 (fluorine-18, F-18, 18F, 18 fluorine), which belongs to positron emission radioisotope, so it becomes 18F-FDG (fluorine - [18F] deoxyglucose). After injecting FDG into the patient (patient, patient), the PET scanner can construct an image reflecting the distribution of FDG in the body. Then, the nuclear medicine physician or radiologist evaluates these images to make a diagnosis of various medical health conditions.

Cefotaxime

MSDS

CAS:63527-52-6

Molecular Formula:C16H17N5O7S2

Alias

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Cefotaxima Acid; (6R,7R)-3-[(Acetyl-Oxy)Methyl]-7-[[(2Z)-(2-Amino-4-Thiazolyl)(Methoxyimino)-Acetyl]Amino]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid; 5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid, 3-[(Acetyloxy)Methyl]-7-[[(2Z)-(2-Amino-4-Thiazolyl)(Methoxyimino)Acetyl]Amino]-8-Oxo-, (6R,7R)-

Brief Introduction

This product is a kind of semi synthetic oxime cephalosporin, which is a pharmaceutical raw material and used as an antibacterial drug.

Clopamide

MSDS

CAS:636-54-4

Molecular Formula:C14H20ClN3O3S

Alias

More Information

Aquex; Brinaldix; Dt-327; Clopamidum; Chlosudimeprimyl; Adurix; 4-Chloro-N-[(2R,6S)-2,6-Dimethylpiperidin-1-Yl]-3-Sulfamoylbenzamide; Clopamidum

Brief Introduction

Clopamide is a thiazide diuretic with oral activity, which can inhibit the sodium coupled chloride cotransporter SLC12A3. Clopamide can be used in the study of hypertension and heart failure.

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