Ethionamide

CAS：536-33-4

Molecular formula: C8H10N2S

Molecular weight: 166.24

Structural type:

Physicochemical properties: Yellow crystal or light yellow powder with weak to medium sulfide smell.

Storage conditions: Low temperature storage, storage temperature is 2 ~ 8 ° C.

Application: Ethiazide is combined with other anti tuberculosis drugs for tuberculosis patients (including relapse), including tuberculous meningitis, treated by first-line drugs (such as streptomycin, isoniazid, rifampicin and ethambutol). It can be used in combination with other leprosy drugs. It can also be used for the treatment of non tuberculous mycobacterial infection, such as bird compound mycobacterial disease.

Properties

Ethionamide is a second line drug in the therapy of tuberculosis used only in combination with other agents and for drug-resistant tuberculosis. Ethionamide has been linked to transient, asymptomatic elevations in serum aminotransferase levels and in uncommon instances of acute liver injury, which can be severe. Ethionamide appears as yellow crystals or canary yellow powder with a faint to moderate sulfide odor. (NTP, 1992)

CAS No.

536-33-4

Formula

C8H10N2S

Molecular Mass

166.24300

Exact Mass

166.05600

PSA

71.00000

Logp

1.97850