2-Aminobenzenethiol

CAS：137-07-5

Molecular formula: C6H7NS

Molecular weight: 125.19

Structural type:

Physicochemical properties: Transparent yellow to amber liquid; Low melting point crystallization. Melting point 19-21 ℃, boiling point 70-72 ℃ / 26.7pa (0.2mmhg), relative density 1.170, refractive index 1.6420, flash point 79 ℃.

Storage conditions: Low temperature storage, storage temperature is 2 ~ 8 ° C.

Application: This product is the intermediate of fostedil. Fostedil is a calcium antagonist containing phosphorus, which has vasodilating and antihypertensive effects. Its activity is similar to diltiazem. It can inhibit the influx of calcium ions into cells by acting on vascular smooth muscle and atrioventricular node of coronary artery and peripheral vessels, thus showing vasodilating effect and prolonging atrioventricular node conduction time. Therefore, it is effective for hypertension, arrhythmia and angina pectoris, But the side effect is less than diltiazem.

Properties

This product is the intermediate of fostedil. Fostedil is a calcium antagonist containing phosphorus, which has vasodilating and antihypertensive effects. Its activity is similar to diltiazem. It can inhibit the influx of calcium ions into cells by acting on vascular smooth muscle and atrioventricular node of coronary artery and peripheral vessels, thus showing vasodilating effect and prolonging atrioventricular node conduction time. Therefore, it is effective for hypertension, arrhythmia and angina pectoris, But the side effect is less than diltiazem.

CAS No.

137-07-5

Formula

C6H7NS

Molecular Mass

125.19100

Exact Mass

125.03000

PSA

64.82000

Logp

2.13870