Meglumine

Product introduction:

Choosing a suitable equilibrium ion for meglumine is particularly important to improve the solubility and bioavailability of drugs. Meglumine is an equilibrium ion widely used to improve drug solubility. It is an amino sugar derived from sorbitol, and its pKa value is 9.6. White crystalline powder. Melting point 128-129 ℃. It is easily soluble in water, slightly soluble in ethanol (1.2g at 25 ℃ and 21g at 70 ℃ in 100ml ethanol), and almost insoluble in chloroform. The taste is slightly sweet and salty.

CAS：6284-40-8

Molecular formula: C₇H₁₇NO₅

Molecular weight: 195.21

Structural type:

Product purpose:

Meglumine can be used as a medical contrast agent, auxiliary agent and surfactant. Meglumine can be used for the preparation and dissolution of contrast agent drugs meglumine diatrizoate and meglumine cholangiopagite, and can also be used as an auxiliary or intermediate of other drugs. Meglumine is an amino sugar derived from sorbitol, which contains amino, primary hydroxyl and secondary hydroxyl. These can activate the reactions of nucleophilic and electrophilic structures in chemical reactions through hydrogen bonds and lone pair electrons, respectively. Because of its special characteristics, such as low toxicity, biodegradability, physiological inertia, reusability, low price and non corrosive properties, meglumine has become an important and efficient catalyst in organic synthesis, which has stimulated more and more research interest in it.