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CAS:357166-30-4
Molecular Formula:C40H48N10Na4O17
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N-[4-[2-(2-Amino-4,7-Dihydro-4-oxo-1H-Pyrrolo[2,3-d]Pyrimidin-5-yl)Ethyl]Benzoyl]-L-Glutamic acid Disodium salt Hydrate; Pemetrexed Sodium Hydrate; Pemetrexed Disodium 2.5 Hydrate; Pemetrexeddisodiumhydrate; Tetrasodium, (2S)-2-[[4-[2-(2-Amino-4-oxo-1,7-Dihydropyrrolo[2,3-d]Pyrimidin-5-yl)Ethyl]Benzoyl]Amino]Pentanedioate,Pentahydrate
Brief Introduction
Pemetrexed Disodium Hydrate is an chemotherapy drug for the treatment of pleural mesothelioma and non-small cell lung cancer. Pemetrexed Disodium Hydrate exhibit inhibitory activities towards thymidylate synthase as well as other folate dependent enzymes.
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CAS:55661-38-6
Molecular Formula:C9H14Cl2N6O2
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1-(4-Amino-2-Methyl-5-Pyrimidinyl)-Methyl-3-(2-Chloroethyl)-3-Nitrosourea Hydrochloride; Nimustine Hcl(Acnu); N'-[(4-Amino-2-Methyl-5-Pyrimidinyl)Methyl]-N-(2-Chloroethyl)-N-Nitrosourea Hydrochloride; 1-(2-Cloroetil)-1-Nitroso-3-((2-Metil-4-Aminopirimidin-5-Il)Metil)Ureaclorhi
Brief Introduction
Nimustine hydrochloride is a pyrimidine nitrourea antitumor drug. Together with other nitrourea drugs, ramustine, carmustine, simustine, lomustine, formustine and estrogen sodium phosphate are the main drugs for the treatment of intracranial tumors and meningeal leukemia. This product is a nitrourea alkylating agent, which can alkylate DNA, prevent DNA repair and change RNA structure, Change the protein and enzyme structure and function of target cells, so as to play an anti-tumor role.
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CAS:571190-30-2
Molecular Formula:C24H29N7O2
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Ibrance(Trade name); Pabcilib; Pabosi Ni
Brief Introduction
Pabcicilib is an inhibitor of cyclin dependent kinase (CDK) 4 and 6. Cyclin D1 and CDK4 / 6 are downstream signaling pathways leading to cell proliferation. In vitro, the proliferation of ER positive breast cancer cells was inhibited by blocking the progression from G1 to S phase. Compared with the treatment of each drug alone, the combination of pabacib and anti estrogen resulted in decreased phosphorylation of retinoblastoma protein (RB), decreased E2F expression and signal, and prevented growth. In vitro treatment of ER positive breast cancer cell lines with combination of pabacib and anti estrogen resulted in increased cell senescence, which lasted up to 6 days after drug removal.
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CAS:877399-52-5
Molecular Formula:C21H22Cl2FN5O
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(R)-Crizotinib; (R)-3-(1-(2,6-Dichloro-3-Fluorophenyl)Ethoxy)-5-(1-(Piperidin-4-yl)-1H-Pyrazol-4-yl)Pyridin-2-Amine; 3-[(1R)-1-(2,6-Dichloro-3-Fluorophenyl)Ethoxy]-5-[1-(4-Piperidinyl)-1H-Pyrazol-4-yl]-2-Pyridinamine; 3-[(1r)-1-(2,6-Dichloro-3-Fluorophenyl)Ethoxy]-5-(1-Piperidin-4-Yl-1h-Pyrazol-4-Yl)Pyridin-2-Amine; 2-Pyridinamine, 3-((1R)-1-(2,6-Dichloro-3-Fluorophenyl)Ethoxy)-5-(1-(4-Piperidinyl)-1H-Pyrazol-4-yl)-
Brief Introduction
Crizotinib is the first accurate drug for non-small cell lung cancer approved by FDA. It is also one of the four fastest developed legendary drugs in the history of cancer drug research and development.
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CAS:989-51-5
Molecular Formula:C22H18O11
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Tea Catechin; (-)-Epigallocatechin Gallate; E-5187; Egcg; Teavigo; Ecgc; Epigallocatechin 3-Gallate; Teavigo Tg; Egcg-D6; (-)-Epigallocatechin Gallate,Egcg
Brief Introduction
Epigallocatechin gallate (EGCG), also known as epigallocatechin-3-gallate. Gallocatechol is an ester formed by gallocatechol and gallic acid, belonging to catechin. EGCG is the most abundant catechin in most famous teas. It could also be antioxidants, which could treat many diseases, including cancer. EGCG is found in green tea, but not in black tea. Because EGCG in black tea is transformed into thearubigin.
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