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Antineoplastic Agents

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CAS:61825-94-3
Molecular Formula:C8H14N2O4Pt
Oxalato(Trans-l-1,2-Cyclohexanediamine)Platinum(II); cis-Oxalato-Trans-l-1,2-Diaminocyclohexaneplatinum(II); [(1S,2S)-2-Azanidylcyclohexyl]Azanide; Oxalate; Platinum(4+)
Brief Introduction
Oxaliplatin, which belongs to platinum derivatives and is clinically used to treat patients with colorectal cancer metastases after failure of fluorouracil treatment, either alone or in combination with fluorouracil, is the third-generation novel platinum based antitumor compound after cisplatin, carboplatin and the only complex platinum based drug with significant activity against colorectal cancer to date. The principle of action is to act on DNA by producing alkylated conjugates, forming intra - and interstrand crosslinks that inhibit DNA synthesis and replication. It also inhibited proliferation in ovarian cancer and melanoma cell lines.
CAS:641571-10-0
Molecular Formula:C28H22F3N7O
Tasigna; Nilotinib (Amn-107); Its Intermediates; Nilotinib For Research; Nilotinib(Amn 107); Nilotinib,Amn107,Tasigna; Amn 107; Nilotinib D6
Brief Introduction
Nilotinib is a new targeted tumor therapeutic drug, which belongs to tyrosine kinase inhibitor. It is used to treat patients with chronic myeloid leukemia (CML) resistant to glipizide (imatinib). Gleevec is the preferred drug developed by Novartis for the treatment of chronic myeloid leukemia (CML). Nilotinib is improved from the molecular structure of imatinib. It has stronger selectivity for bcr-abl kinase activity. Its inhibitory effect on tyrosine kinase is 30 times stronger than imatinib. It can inhibit the kinase activity of BCR-ABL mutant resistant to imatinib. It can also inhibit kit and PDGFR kinase activities.
CAS:69-74-9
Molecular Formula:C9H14ClN3O5
1-β-D-Arabinofuranosylcytosine Hydrochloride; 4-Amino-1-[3,4-Dihydroxy-5-(Hydroxymethyl)-2-Tetrahydrofuranyl]-2-Pyrimidinone; 4-Amino-1-[3,4-Dihydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-Yl]Pyrimidin-2(1H)-One; 4-Amino-1-[3,4-Dihydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-Yl]Pyrimidin-2-One; Cytosine-Beta-D-Arabinofuranose Hydrochloride
Brief Introduction
Cytarabine Hydrochloride is a pyrimidine antimetabolic drug, which is mainly used to treat acute myeloid leukemia and gastrointestinal tumors. It is the most common drug for the treatment of leukemia. It has been widely used in clinic for a long time and achieved good therapeutic effect
CAS:10212-25-6
Molecular Formula:C9H12ClN3O4
2,2'-Anhydro-(1-β-D-Arabinofuranosyl)Cytosine Hydrochloride; 2,2'-Anhydro-1-Beta-D-Arabinofuranosylcytosine Hydrochloride; 1-Beta-D-Arabinofuranosyl-2,2'-Anhydro-Cytosinhydrochloride; Cyclocytidine HCL , Cytidine; O-2,2'-Cyclocytidinemonohydrochloride; (2R,4R,5R,6S)-4-(Hydroxymethyl)-10-Imino-3,7-Dioxa-1,9-Diazatricyclo[6.4.0.02,6]Dodeca-8,11-dien-5-ol;Hydrochloride
Brief Introduction
Ancitabine Hydrochloride is effective for all types of acute leukemia and meningeal leukemia.
CAS:105826-92-4
Molecular Formula:C17H21ClN2O2
(3-Endo)-8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl 1H-Indole-3-Carboxylate Hydrochloride; 3-Tropanylindole-3-Carboxylate Hydrochloride; (3-Endo)-8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl 1H-Indole-3-Carboxylic Acid Ester Monohydrochloride; Tropisetron Hydrochloride 98.5-101.5%; Tropisetronhcl/Mesylate; Tropisetron HCL
Brief Introduction
For the treatment of nausea and vomiting due to chemotherapy and radiotherapy
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