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Antineoplastic Agents

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CAS:641571-10-0
Molecular Formula:C28H22F3N7O
Tasigna; Nilotinib (Amn-107); Its Intermediates; Nilotinib For Research; Nilotinib(Amn 107); Nilotinib,Amn107,Tasigna; Amn 107; Nilotinib D6
Brief Introduction
Nilotinib is a new targeted tumor therapeutic drug, which belongs to tyrosine kinase inhibitor. It is used to treat patients with chronic myeloid leukemia (CML) resistant to glipizide (imatinib). Gleevec is the preferred drug developed by Novartis for the treatment of chronic myeloid leukemia (CML). Nilotinib is improved from the molecular structure of imatinib. It has stronger selectivity for bcr-abl kinase activity. Its inhibitory effect on tyrosine kinase is 30 times stronger than imatinib. It can inhibit the kinase activity of BCR-ABL mutant resistant to imatinib. It can also inhibit kit and PDGFR kinase activities.
CAS:656247-18-6
Molecular Formula:C33H39N5O7S
3-Z-[1-(4-(N-((4-Methyl-Piperazin-1-Yl)-Methylcarbonyl)-N-Methyl-Amino)-Anilino)-1-Phenyl-Methylene]-6-Methoxycarbonyl-2-Indolinone Monoethanesulphonate; Ethanesulfonic Acid - Methyl (3Z)-3-{[(4-{Methyl[(4-Methyl-1-Pipe Razinyl)Acetyl]Amino}Phenyl)Amino](Phenyl)Methylene}-2-Oxo-6-Indo Linecarboxylate (1:1); Methyl (3Z)-3-[({4-[N-Methyl-2-(4-Methylpiperazin-1-Yl)Acetamido]Phenyl}Amino)(Phenyl)Methylidene]-2-Oxo-2,3-Dihydro-1H-Indole-6-Carboxylate Ethanesulfonate Salt; 3-Z-[1-(4-(N-((4-Methyl-Piperazin-1-Yl)-Methylcarbonyl)-N-Methyl-Amino)-Anilino)-1-Phenyl-Methylene]-6-Methoxycarbonyl-2-Indolinone Monoethanesulfonate Salt; (3S,5S)-3,5-Bis[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-1-Hydroxy-Cyclohexanecarboxylic Acid Methyl Ester
Brief Introduction
Nitanib ethylsulfonate is a small molecule inhibitor of multi receptor tyrosine kinase and non receptor tyrosine kinase. In 2014, it was approved by FDA for the first time, and was developed and sold by bringer Ingelheim company for the first time. It has been approved by the US Food and Drug Administration (FDA), the European Drug Administration (EMA) and the agency for drugs and medical devices (PMDA) for the treatment of idiopathic pulmonary fibrosis, and by EMA for non-small cell lung cancer.
CAS:69-74-9
Molecular Formula:C9H14ClN3O5
1-β-D-Arabinofuranosylcytosine Hydrochloride; 4-Amino-1-[3,4-Dihydroxy-5-(Hydroxymethyl)-2-Tetrahydrofuranyl]-2-Pyrimidinone; 4-Amino-1-[3,4-Dihydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-Yl]Pyrimidin-2(1H)-One; 4-Amino-1-[3,4-Dihydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-Yl]Pyrimidin-2-One; Cytosine-Beta-D-Arabinofuranose Hydrochloride
Brief Introduction
Cytarabine Hydrochloride is a pyrimidine antimetabolic drug, which is mainly used to treat acute myeloid leukemia and gastrointestinal tumors. It is the most common drug for the treatment of leukemia. It has been widely used in clinic for a long time and achieved good therapeutic effect
CAS:10212-25-6
Molecular Formula:C9H12ClN3O4
2,2'-Anhydro-(1-β-D-Arabinofuranosyl)Cytosine Hydrochloride; 2,2'-Anhydro-1-Beta-D-Arabinofuranosylcytosine Hydrochloride; 1-Beta-D-Arabinofuranosyl-2,2'-Anhydro-Cytosinhydrochloride; Cyclocytidine HCL , Cytidine; O-2,2'-Cyclocytidinemonohydrochloride; (2R,4R,5R,6S)-4-(Hydroxymethyl)-10-Imino-3,7-Dioxa-1,9-Diazatricyclo[6.4.0.02,6]Dodeca-8,11-dien-5-ol;Hydrochloride
Brief Introduction
Ancitabine Hydrochloride is effective for all types of acute leukemia and meningeal leukemia.
CAS:105826-92-4
Molecular Formula:C17H21ClN2O2
(3-Endo)-8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl 1H-Indole-3-Carboxylate Hydrochloride; 3-Tropanylindole-3-Carboxylate Hydrochloride; (3-Endo)-8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl 1H-Indole-3-Carboxylic Acid Ester Monohydrochloride; Tropisetron Hydrochloride 98.5-101.5%; Tropisetronhcl/Mesylate; Tropisetron HCL
Brief Introduction
For the treatment of nausea and vomiting due to chemotherapy and radiotherapy
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