Sinefungin is an effective inhibitor of viral mRNA (guanine-7 -) - methyltransferase, mRNA (nucleoside - 2 '-) - methyltransferase and viral proliferation. Sinefungin is a SET7/9 inhibitor, which can improve renal fibrosis by inhibiting H3K4 methylation.

Oteseconazole

CAS:1340593-59-0

Molecular Formula:C23H16F7N5O2

Brief Introduction

Oteseconazole is an oral fungal CYP51 inhibitor, and its selectivity to fungal CYP51 is significantly better than the existing commonly used azole drugs.

Osilodrostat

CAS:928134-65-0

Molecular Formula:C13H10FN3

Alias

More Information

Isturisa; (+)-Osilodrostat; (R)-4-(6,7-Dihydro-5H-Pyrrolo[1,2-c]Imidazol-5-yl)-3-Fluorobenzonitrile; 4-[(5R)-6,7-Dihydro-5H-Pyrrolo[1,2-c]Imidazol-5-yl]-3-Fluorobenzonitrile; 4-[(4R,5R)-6,7-Dihydro-5H-Pyrrolo[1,2-c]Imidazol-5-yl]-3-Fluorobenzonitrile; Benzonitrile, 4-((5R)-6,7-Dihydro-5H-Pyrrolo(1,2-c)Imidazol-5-yl)-3-Fluoro-; C1CC2=CN=CN2[C@H]1C3=C(C=C(C=C3)C; N)F

Brief Introduction

Osilodrostat is a man 11 β- It is an effective inhibitor of hydroxylase and aldosterone synthetase.

Lurbinectedin

CAS:497871-47-3

Molecular Formula:C41H44N4O10S

Alias

More Information

Tryptamicidin; Zepzelca; [(1R,2R,3R,11S,12S,14R,26R)-5,12-Dihydroxy-6,6'-Dimethoxy-7,21,30-Trimethyl-27-Oxospiro[17,19,28-Trioxa-24-thia-13,30-Diazaheptacyclo[12.9.6.13,11.02,13.04,9.015,23.016,20]Triaconta-4(9),5,7,15,20,22-Hexaene-26,1'-2,3,4,9-Tetrahydropyrido[3,4-b]Indole]-22-yl] Acetate; Zepsyre; (1'R,6R,6AR,7R,13S,14S,16R)-8,14-Dihydroxy-6',9-Dimethoxy-4,10,23-Trimethyl-19-OXO-2',3',4',6,7,9',12,13,14,16-Decahydro-6Ahspiro(7,13-Azano-6,16-(Epithiopropanooxymethano)(1,3)Dioxolo(7,8)Isoquinolino(3,2-B)(3)Benzazocine-20,1'-Pyrido(3,4-B)Indol)-5-YL Acetate; [(1R,2R,3R,11S,12S,14R,26R)-5,12-Dihydroxy-6,6'-Dimethoxy-7,21,30-Trimethyl-27-Oxospiro[17,19,28-Trioxa-24-thia-13,30-Diazaheptacyclo[12.9.6.13,11.02,13.04,9.015,23.016,20]Triaconta-4(9),5,7,15,20,22-Hexaene-26,1'-2,3,4,9-Tetrahydropyrido[3,4-b]Indole]-22; Spiro(6,16-(Epithiopropanoxymethano)-7,13-Imino-12H-1,3-Dioxolo(7,8)Isoquino(3,2-B)(3)Benzazocine-20,1'-(1H)Pyrido(3,4-B)Indol)-19-ONE, 5-(Acetyloxy)-2',3',4',6,6A,7,9',13,14,16-Decahydro-8,14-Dihydroxy-6',9-Dimethoxy-4,10,23-Trimethyl-, (1'R,6R,6AR,7R,13S,14S,16R)-; Lurbinectidine

Brief Introduction

Lurbinectedin is a new covalent adhesive for small DNA grooves, which has high antitumor activity.

Adagrasib

CAS:2326521-71-3

Molecular Formula:C32H35ClFN7O2

Alias

More Information

MRTX849; MRTX-849; 2-((S)-4-(7-(8-Chloronaphthalen-1-yl)-2-(((S)-1-Methylpyrrolidin-2-yl)Methoxy)-5,6,7,8-Tetrahydropyrido[3,4-d]Pyrimidin-4-yl)-1-(2-Fluoroacryloyl)Piperazin-2-yl)Acetonitrile; 2-[(2S)-4-[7-(8-Chloronaphthalen-1-yl)-2-[[(2S)-1-Methylpyrrolidin-2-yl]Methoxy]-6,8-Dihydro-5H-Pyrido[3,4-d]Pyrimidin-4-yl]-1-(2-Fluoroprop-2-Enoyl)Piperazin-2-yl]Acetonitrile; 2-Piperazineacetonitrile, 4-[7-(8-Chloro-1-Naphthalenyl)-5,6,7,8-Tetrahydro-2-[[(2S)-1-Methyl-2-Pyrrolidinyl]Methoxy]Pyrido[3,4-d]Pyrimidin-4-yl]-1-(2-Fluoro-1-oxo-2-Propen-1-yl)-, (2S)-; ((2S)-4-(7-(8-Chloronaphthalen-1-YL)-2-(((2S)-1- Methylpyrrolidin-2-YL)Methoxy)-5,6,7,8- Tetrahydropyrido(3,4-D)Pyrimidin-4-YL)-1-(2-Fluoroprop2-Enoyl)Piperazin-2-YL)Acetonitrile; [(2S)-4-[7-(8-Chloro-1-Naphthyl)-2-{[(2S)-1-Methyl-2-Pyrrolidinyl]Methoxy}-5,6,7,8-Tetrahydropyrido[3,4-d]Pyrimidin-4-yl]-1-(2-Fluoroacryloyl)-2-Piperazinyl]Acetonitrile

Brief Introduction

MRTX849 is an effective, orally available, mutation selective KRAS G12C covalent inhibitor with potential anti-tumor activity.

1
···
20
21
22
23
24
25
26
···
29

Inquiry (

/ 10

)

Clear All