[3H]-Rilpivirine; Edurant; Tmc-278; 4-[[4-[4-[(E)-2-Cyanoethenyl]-2,6-Dimethylanilino]Pyrimidin-2-Yl]Amino]Benzonitrile; Unii-Fi96A8X663; Rilpivirine free base

Brief Introduction

Rilpivirine is an aminopyrimidine that is pyrimidine-2,4-diamine in which the amino groups at positions 2 and 4 are substituted by 4-cyanophenyl and 4-[(E)-2-cyanovinyl]-2,6-dimethylphenyl groups respectively. Used for treatment of HIV. It has a role as a HIV-1 reverse transcriptase inhibitor and an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor. It is a nitrile and an aminopyrimidine. It is a conjugate base of a rilpivirine(1+).

Histamine Dihydrochloride

MSDS

CAS:56-92-8

Molecular Formula:C5H11Cl2N3

Alias

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Bichlorhydrated’Histamine; Edihydrochlorideavailablefrom1Kgto100Kg.; Histaminedichloride; 1H-Imidazole-4-Ethanamine Dihydrochloride; 2-(1H-Imidazol-4-Yl)Ethanamine; 2-(1H-Imidazol-4-Yl)Ethanamine Dihydrochloride

Brief Introduction

Histamine dihydrochloride is used for continuous remission and prevention of relapse after first remission in adult patients with acute myeloid leukemia (AML).

Capmatinib

CAS:1029712-80-8

Molecular Formula:C23H17FN6O

Alias

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Benzamide,2-Fluoro-N-Methyl-4-[7-(6-Quinolinylmethyl)Imidazo[1,2-B][1,2,4]Triazin-2-Yl]-; 2-Fluoro-N-Methyl-4-[7-[(Quinolin-6-Yl)Methyl]Imidazo[1,2-B]-[1,2,4]Triazin-2-Yl]Benzamide Capmatinib;

Brief Introduction

Camatinib can effectively inhibit the proliferation and migration of c-met dependent tumor cells and induce apoptosis. It has antitumor activity.

2-(4-(4-Chloro-1,2-Diphenyl-But-1-Enyl)Phenoxy)Ethanol

CAS:128607-22-7

Molecular Formula:C24H23ClO2

Alias

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2-[4-[(1Z)-4-Chloro-1,2-Diphenyl-1-Buten-1-Yl]Phenoxy]-Ethanol; 2-(P-((Z)-4-Chloro-1,2-Diphenyl-1-Butenyl)Phenoxy)Ethanol; Ccris 9205; Fc-1271A; Ospemifene; Unii-B0P231Ilbk; 2-[4-[(Z)-4-Chloro-1,2-Diphenylbut-1-Enyl]Phenoxy]Ethanol

Kpt-330

CAS:1393477-72-9

Molecular Formula:C17H11F6N7O

Alias

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(2Z)-3-[3-[3,5-Bis(Trifluoromethyl)Phenyl]-1H-1,2,4-Triazol-1-Yl]-2-Propenoic Acid 2-(2-Pyrazinyl)Hydrazide; Selenixor; Selinexor; Selinexor (Kpt-330); (Z)-3-(3-(3,5-Bis(Trifluoromethyl)Phenyl)-1H-1,2,4-Triazol-1-Yl)-N'-(Pyrazin-2-Yl)Acrylohydrazide; 2-Propenoic Acid, 3-[3-[3,5-Bis(Trifluoromethyl)Phenyl]-1H-1,2,4-Triazol-1-Yl]-, 2-(2-Pyrazinyl)Hydrazide, (2Z)-; Aloradine; Kpt330,Selinexor

Brief Introduction

In July 2019, Celinosol (trade name: Xpovio) was approved for sale in the United States, becoming the world's first and only selective nuclear export inhibitor. Subsequently, Selinso was approved for listing in Israel, the United Kingdom, and EU countries.

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