Tezosentan; 2-Pyridinesulfonamide,N-(6-(2-Hydroxyethoxy)-5-(2-Methoxyphenoxy)-2-(2-(1H-Tetrazol-5-Yl)-4-Pyridinyl)-4-Pyrimidinyl)-5-(1-Methylethyl); Tezosentan [Inn]; N-(6-(2-Hydroxyethoxy)-5-(2-Methoxyphenoxy)-2-(2-(1H-Tetrazol-5-Yl)-4-Pyridinyl)-4-Pyrimidinyl)-5-(1-Methylethyl)-2-Pyridinesulfonamide; Unii-64J9J55263; Chembl61780

Brief Introduction

A potent dual endothelian (ETA/ETB) receptor antagonist optimized from Bosentan. It is used in the treatment of congestive heart failure.

Bromazine Hydrochloride

CAS:1808-12-4

Molecular Formula:C17H21BrClNO

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Bromdiphenhydramine Hydrochloride; Bromdiphenylhydramine Hydrochloride; Einecs 217-310-9; [2-(4-Brom-Benzhydryloxy)-Aethyl]-Dimethyl-Amin,Hydrochlorid; Phenyl(P-Bromophenyl)(Dimethylaminoethoxy)Methane Hydrochloride; [2-(4-Bromo-Benzhydryloxy)-Ethyl]-Dimethyl-Amine,Hydrochloride; Bromodiphenhydramine Hcl; Ethanamine, 2-[(4-Bromophenyl)Phenylmethoxy]-N,N-Dimethyl-, Hydrochloride; 2-[(4-Bromophenyl)Phenylmethoxy]Ethyl(Dimethyl)Ammonium Chloride; 2-[(4-Bromophenyl)-Phenylmethoxy]Ethyl-Dimethylazanium,Chloride; Bromodiphenhydramine Hydrochloride; 2-[(4-Bromophenyl)Phenylmethoxy]-N,N-Dimethyl-Ethanamine,Hydrochloride

Brief Introduction

Antihistaminic.

Lasofoxifene

CAS:180916-16-9

Molecular Formula:C28H31NO2

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Lasofoxifen; Oporia; Cp 336156; Lasofoxifene Tartrate

Brief Introduction

Lasofoxifene (INN) (brand name Fablyn) is a non-steroidal selective estrogen receptor modulator (SERM) which is marketed by Pfizer for the prevention and treatment of osteoporosis and for the treatment of vaginal atrophy, and the result of an exclusive research collaboration with Ligand Pharmaceuticals (LGND). It also appears to have had a statistically significant effect of reducing breast cancer in women according to a study published in The Journal of the National Cancer Institute.

2-[2-(Diethylamino)Ethoxy]Ethyl 2-Phenylbutanoate

CAS:18109-80-3

Molecular Formula:C18H29NO3

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Butamirato; Butamiratum; Brospamin; Butamirate; Butamyrate

Brief Introduction

Butamirate (or brospamin) is a cough suppressant.A study found it to bind to the cough center in the medulla oblongata, more specifically the dextromethorphan-binding site in guinea pig brain with high affinity.

Valdecoxib

CAS:181695-72-7

Molecular Formula:C16H14N2O3S

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4-(5-Methyl-3-Phenylisoxazol-4-Yl)Benzensulfonamide; Kudeq; 4-(4-Sulfamoylphenyl)-5-Methyl-3-Phenyl-Isoxazole; Valdyn; 4-(5-Methyl-3-Phenyl-1,2-Oxazol-4-Yl)Benzenesulfonamide; 4-(5-Methyl-3-Phenyl-4-Isoxazolyl)Benzenesulfonamide; Bextra; 4-[5-Methyl-3-Phenylisoxazol-4-Yl ] Benzenesulfonamide; Valdecoxib(R); [14C]-Valdecoxib

Brief Introduction

Vardixib is not only the key intermediate in the synthesis of parecoxib sodium, but also its main hydrolysate. It is the main impurity in the inspection of related substances of parecoxib sodium. Parecoxib is a non steroidal anti-inflammatory drug. It is an amide precursor (water-soluble precursor) of varcoxib, a highly selective COX-2 inhibitor. After intravenous administration, parecoxib is rapidly hydrolyzed by carboxylesterase to varcoxib, which plays an anti-inflammatory and analgesic role.

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