Castanospermine Castanospermum Australe Seeds; Tanospermine From Tanospermum*Australe Seed; Castanospermine From Castanospermum Austral; Castanospermine; Exatecan Monomethanesulfonate; 1,6,7,8-Tetrahydroxyoctahydroindolizine; Tanospermine,Tanospermum Australe; Exatecan Free Base; Unii-Oc71Pp0F89; Dx-8951F

Brief Introduction

Exatecan (DX-8951) is a DNA topoisomerase I inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL), which can be used in cancer research.

Sodium Phenylbutyrate

CAS:1716-12-7

Molecular Formula:C10H11NaO2

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Sodium Phenylbutyrate; 4-Pba,4-Phenylbutyric Acid,4-Phenylbutyrate; Sodium 4-Phenylbutyrate; Sodium 4-Phenylbutanoate; Buphenyl

Brief Introduction

Pharmaceutical intermediates and other fine chemical products.

2-Amino-4-[[(2S,3S,4R,5R)-5-(6-Aminopurin-9-Yl)-3,4-Dihydroxyoxolan-2-Yl]Methyl-Methylsulfonio]Butanoate

CAS:17176-17-9

Molecular Formula:C22H30N6O8S2

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Sam P-Toluenesulfonate Salt; Methionine,S-Adenosyl-,Dl; S-Adenosyl-Dl-Methionine; S-Adenosyl Methionione; Methyl-S-Adenosyl-L-Met; Adomet Sam P-Toluenesulfonate Salt; Ademethionine; S-(5'-Adenosyl)-L-Methionine P-Toluenesulfonate Salt; S-(5'-Deoxyadenosine-5'-Yl)Methionine; S-(5'-Deoxyadenosine-5'-Yl); Sam-E; Ademetionine

Brief Introduction

S-Adenosyl-DL-methionine is an organic compound, which is a white powder. It is endogenous produced by methionine and ATP through the action of methionine adenosyltransferase. It is an important methyl donor with oral activity. S-Adenosyl-DL-methionine is a dietary supplement with antidepressant and analgesic effects, which can be used in the study of liver disease and osteoarthritis.

Fosaprepitant

CAS:172673-20-0

Molecular Formula:C23H22F7N4O6P

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[3-{[(2R,3S)-2-[(1R)-1-[3,5-Bis(Trifluoromethyl)Phenyl]Ethoxy]-3-(4-Fluorophenyl)Morpholin-4-Yl]Methyl}-5-Oxo- 2H-1,2,4-Triazol-1-Yl]Phosphonic Acid; Phosphonic Acid, [3-[[2-[1-[3,5-Bis(Trifluoromethyl)Phenyl]Ethoxy]-3-(4-Fluorophenyl)-4-Morpholinyl]Methyl]-2,5-Dihydro-5-Oxo-1H-1,2,4-Triazol-1-Yl]-, [2R-[2α(R*),3α]]-; Unii-6L8Of9Xrdc; Ivemend®; Phosphonic Acid, [3-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(Trifluoromethyl)Phenyl]Ethoxy]-3-(4-Fluorophenyl)-4-Morpholinyl]Methyl]-2,5-Dihydro-5-Oxo-1H-1,2,4-Triazol-1-Yl]- (9Ci); [5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(Trifluoromethyl)Phenyl]Ethoxy]-3-(4-Fluorophenyl)Morpholin-4-Yl]Methyl]-3-Oxo-1H-1,2,4-Triazol-2-Yl]Phosphonic Acid; L 758298; L-758,298; P-[3-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(Trifluoromethyl)Phenyl]Ethoxy]-3-(4-Fluorophenyl)-4-Morpholinyl]Methyl]-2,5-Dihydro-5-Oxo-1H-1,2,4-Triazol-1-Yl]Phosphonic Acid; Phosphonic Acid, P-[3-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(Trifluoromethyl)Phenyl]Ethoxy]-3-(4-Fluorophenyl)-4-Morpholinyl]Methyl]-2,5-Dihydro-5-Oxo-1H-1,2,4-Triazol-1-Yl]-; Emend® (For Injection)

Brief Introduction

Fosaprepitant (l-758298) is a prodrug of aprepotant (hy-10052). Fosaprepitant, a neurokinin-1 receptor antagonist, was developed to prevent chemotherapy-induced nausea and vomiting (CINV).

Benzoic Acid, 4-Fluoro-, 8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl Ester, Exo- (9Ci)

CAS:172883-97-5

Molecular Formula:C15H18FNO2

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4-Fluorotropacocaine; [(1S,5R)-8-Methyl-8-Azabicyclo[3.2.1]Octan-3-Yl] 4-Fluorobenzoate; Unii-5S4Mzz9Ya2; 5S4Mzz9Ya2

Brief Introduction

3β-(p-Fluorobenzoyloxy)tropane, (8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 4-fluorobenzoic acid ester, 4-fluorotropacocaine, 3-Pseudotropyl-4-fluorobenzoate, 3-pseudotropyl-4-fluorobenzoate, pFBT) is a tropane derivative drug which acts as a local anaesthetic, having around 30% the stimulant potency of cocaine but around the same potency as a local anaesthetic. It has been investigated as a potential radiolabelled agent for studying receptor binding, but was not adopted for this application. The main application for fluorotropacocaine however has been as a designer drug analogue of cocaine, first detected by the EMCDDA in 2008, and subsequently sold as an ingredient of various "bath salt" powder products, usually mixed in combination with other stimulant drugs such as caffeine, dimethocaine, desoxypipradrol or substituted cathinone derivatives.

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