Pharmaceutical Raw Materials

Pyridoxal phosphate is the coenzyme form of vitamin B6. In the catalytic reaction, the intramolecular aldehyde group of pyridoxal phosphate and α- The amino combination of amino acids first forms aldehyde imine, also known as Schiff base, and then turns amino acids into ammonia, decarboxylation or racemization according to the characteristics of different enzyme proteins. As a coenzyme of amino acid transaminase, decarboxylase and racemic enzyme, it plays a very important role in amino acid metabolism. Pyridoxal phosphate is an important substance in pyridoxal. It is not only the coenzyme of aminotransferase and decarboxylase in amino acid metabolism, but also promotes the decarboxylation of glutamic acid and promotes the γ- Aminobutyric acid production. Pyridoxal phosphate in synthesis β- Carbonylamide drugs, biological activity research and other fields are also widely used, such as clinically, it is mainly used to treat Parkinson's disease, promote transaminase transamination, and improve the content of dopamine in the body.

M-hydroxylamine mainly acts on α Receptors, right β The effect of 1 receptor is weak; Part of the effect is by promoting the release of norepinephrine from sympathetic terminals. It is suitable for the early treatment of shock and the prevention and treatment of acute hypotension during spinal anesthesia. It can also be used for the auxiliary symptomatic treatment of hypotension caused by bleeding, drug allergy, surgical complications, brain trauma or brain tumor combined with shock, and also for the treatment of hypotension caused by cardiogenic shock or sepsis.

3,4-diaminopyridine is a pyridine organic compound, which can be used as pharmaceutical intermediate and organic synthesis intermediate. It is mainly used in laboratory R & D process and chemical production process.

Progesterone contraceptives have strong anti estrogen activity and can inhibit ovulation and gonadotropin secretion. Used to prevent pregnancy.

Etonogestrel (Implanon, nexplanon, 3-oxodesogestrel, 3-keto-desogestrel) is the synthesis of natural progesterone. In the reproductive system, it can bind the cytoplasmic progesterone receptor and activate the gene expression mediated by progesterone receptor.