Tiomolibdate Choline is an orally active second generation tetrathiomolybdate analog with anti-angiogenic and antineoplastic activities. Tiomolibdate choline selectively chelates the copper ion in superoxide dismutase 1 (SOD1) in endothelial cells, thereby depleting SOD1 of copper and inhibiting its activity. Inhibition of SOD1 interferes with the activation of several signal transduction pathways required for cellular proliferation and angiogenesis, including those mediated by ERK1/2 and FAK and Src kinases. This results in an inhibition of cell proliferation and angiogenesis as well as induction of apoptosis.

Phentolamine Mesylate

MSDS

CAS:65-28-1

Molecular Formula:C18H23N3O4S

Alias

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Phentolamine Mesilate; Regitin; Regitin Mesylate; Phentolamine Methanesulfonate; Phentolamine Methanesulfonate Salt; Vasomax; M-(N-(2-Imidazolin-2-Ylmethyl)-P-Toluidino)-Phenomonomethanesulfonate(Sal

Brief Introduction

Phentolamine mesylate is a short acting nonselective A-receptor blocker, which can antagonize the effects of epinephrine and norepinephrine in blood circulation, dilate blood vessels and reduce the resistance of peripheral blood vessels. It has antagonistic catecholamine effect and is used in the diagnosis and treatment of pheochromocytoma, but it has little effect on the blood pressure of normal people or patients with essential hypertension. It can also reduce the peripheral vascular resistance, reduce the cardiac afterload, decrease the left ventricular end diastolic pressure and pulmonary artery pressure, and increase the cardiac stroke volume. It can be used in the treatment of heart failure. Carcinogenic, mutagenic and reproductive toxicity.

Ctp

MSDS

CAS:65-47-4

Molecular Formula:C9H16N3O14P3

Alias

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Cytosine-5'-Triphosphate; Cytidinetriphosphate; Cytidine 5'-(Tetrahydrogen Triphosphate); Cytidine Triphosphate-Na2; 5’-Ctp; Cytidine3’-Triphosphate; [[[(2R,3S,4R,5R)-5-(4-Amino-2-Oxo-1-Pyrimidinyl)-3,4-Dihydroxy-2-Oxolanyl]Methoxy-Oxidophosphoryl]Oxy-Oxidophosphoryl] Phosphate; Cytidine 5'-Triphosphate

Brief Introduction

Cytidine triphosphate (CTP) is a nucleotide that is one of the starting materials for the synthesis of RNA. CTP is as high energy molecule as ATP, but less as energy source compared to ATP. CTPs can be involved in the synthesis of glycerophospholipids or the glycosylation of proteins.

Sulfamethoxydiazine

MSDS

CAS:651-06-9

Molecular Formula:C11H12N4O3S

Alias

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Sulfameter; Sulfamethoxy-Diazine; Sulfamethoxine; 4-Amino-N-(5-Methoxypyrimidin-2-Yl)Benzenesulfonamide; 5-Methoxysulfadiazine; Ultrax; Sulphamethoxydiazine; Sulfametin; Sulfamethoxypyrimidine; Sulfametoxydiazine; Sulphameter

Brief Introduction

It is mainly used to prevent and treat infections caused by hemolytic streptococcus, pneumococcus and meningococcus. Treat coccidiosis, urinary tract and respiratory tract infection.

Mitoxantrone

MSDS

CAS:65271-80-9

Molecular Formula:C22H28N4O6

Alias

More Information

[3H]-Mitoxantrone; Mitoxantronum; Dihydroxyanthraquinone; 1,4-Dehydroxy-5,8-Bis[[[2-(2-Hydroxyethyl)Amino]Ethyl]Amino]-9,19-Antracenedion; Mitoxantronum And The Intermediates; Mitoxanthrone; Pharmasubstanceep4; 1,4-Bis-[2-(2-Hydroxyethylamino)Ethylamino]-5,8-Dihydroxy-9,10-Anthracenedione; 1,4-Bis[2-(2-Hydroxyethylamino)Ethylamino]-5,8-Dihydroxyanthraquinone; 1,4-Dihydroxy-5,8-Bis[[2-(2-Hydroxy-Ethylamino)Ethyl]Amino]Anthraquinone

Brief Introduction

Anthracycline anticancer drugs have similar or slightly higher anticancer activity than adriamycin, which is significantly higher than cyclophosphamide, cytarabine, methotrexate, fluorouracil, vincristine and other commonly used anticancer drugs. Clinically, it is effective for breast cancer.

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