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Sichuan Neijiang Huixin Pharmaceutical Co., Ltd.

23 YRS

Sichuan, China

CNY 3 Million

53280 m²

Less than 50 people

Main Products: Vitamin D2 / Ergosterol / Vitamin D3 / Calcipotriene / Calcitriol / Alfacalcidol

Sichuan, China

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Alfacalcidol / CAS 41294-56-8

OVERVIEW

Packaging

25 KG/Fibre Drum

Lead Time

14-30 days

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DESCRIPTION

Alfacalcidol

IUPAC name: (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-7a-Methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol

Other name: Alphacalcidol; 1-Hydroxycholecalciferol

CAS No.: 41294-56-8

Molecular Formula: C₂₇H₄₄O₂

Molecular weight: 400.64

Alias: Alfa D3; alpha-hydroxy vitamin D3

Pharmacology action : To increase the weight of the small intestine and kidney tubules, inhibit parathyroid hyperplasia, reduce parathyroid hormone synthesis and release, inhibit bone resorption; increase the synthesis of transforming growth factor -I (TGF-) and insulin like growth factor (IGF-I).

Typical Properties

Alfacalcitol is a white crystalline or crystalline powder, insoluble in water and hexane, and soluble in methanol, absolute ethanol, chloroform, dichloromethane, acetone or ether. It is easy to deteriorate in case of air and light. Alfacalcitol was first developed by the American bone health international company . Alfacalcitol is mostly used for calcium metabolism disorder caused by vitamin D metabolism disorder. It is clinically used to treat osteoporosis, chronic renal insufficiency, hypothyroidism, anti vitamin D rickets, osteomalacia, etc.

CAS No.

41294-56-8

Formula

C27H44O2

Molecular Mass

400.63700

Exact Mass

400.33400

PSA

40.46000

Logp

6.58980

IUPAC

(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol

SMILES

C[C@H](CCCC(C)C)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C/C=C/3\C[C@H](C[C@@H](C3=C)O)O)C

Matter Classification

organic

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