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Introduction:
Tetracaine hydrochloride is a highly effective local anesthetic that can block nerve function reversibly. It is used in infiltration anesthesia, nerve block anesthesia, epidural anesthesia, etc. compared with procaine, its local anesthesia effect is significant and has been widely used in clinic. It is found that the synthesis of intermediate p-butylamino benzoic acid is the key step in the synthesis of tetracaine hydrochloride, which has the disadvantages of unstable raw materials or low yield.
CAS：136-47-0
Molecular formula: C15H25ClN2O2
Molecular weight: 300.82
Structural type:
Product Application:
This product is a long-acting ester local anesthetic. Its function is characterized by strong penetration to mucosa. It is suitable for surface anesthesia. There are no adverse reactions such as vasoconstriction, mydriasis and corneal injury after eye drops. It is commonly used in ophthalmology. The effect and toxicity of local anesthesia are about 10 times greater than procaine. After injection, the anesthetic effect was slow (about 10 minutes), and the metabolism was also slow after absorption. The local anesthesia time was up to 3ij, h, - J. about. It is mainly used for surface anesthesia of eye, nose and throat mucosa, and rarely used for conduction anesthesia and epidural anesthesia. Because of its high toxicity, it is generally not used for infiltration anesthesia.
Manufacturing
