Introduction:
Crisaborole is a PDE4 inhibitor. PDE4 activity is increased in circulating inflammatory cells in patients with atopic dermatitis. PDE4 is a very core regulatory point for the production of inflammatory cytokines in atopic dermatitis, mainly through the degradation of cyclic adenosine monophosphate.
CAS:906673-24-3
Molecular formula: C14H10BNO3
Molecular weight: 251.04
Structural type:
Product Application:
The biggest advantage of clenbuterol is that it is a small molecule non hormone drug, which can achieve the combination of therapeutic effect and comfort, and even has almost no side effects for some patients. It is the first external drug of dermatology to enter the list of clinically urgently needed new drugs. It can be said that the listing of clenbuterol fills the treatment needs of Chinese children and adults with atopic dermatitis, breaking the current situation that there are no new products in the field of topical non hormonal anti-inflammatory for more than 10 years, which is of epoch-making significance.