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CAS:112809-51-5
Molecular Formula:C17H11N5
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Letrozoleusp28; Cgs-20267; Letrazole; Letrozolex; Lelrozol; 1-[Bis(4-Cyanophenyl)Methyl]-1,2,4-Triazole; 4,4'-(1H-1,2,4-Triazol-1-Ylmethylene)Dibenzonitrile; Femara; 4,4'-(1H-1,2,4-Triazol-1-Ylmethylene)bis(Benzonitrile); UNII-7LKK855W8I; 4,4'-((1h-1,2,4-Triazol-1-yl)Methylene)Dibenzonitrile; Letrozol; Letoval; 4,4'-(1H-1,2,4-Triazol-1-Ylmethylene)Bisbenzonitrile; Femera; [14C]-Letrozole; 4-[(4-Cyanophenyl)-(1,2,4-Triazol-1-yl)Methyl]Benzonitrile
Brief Introduction
Letrozole is a new generation of highly selective aromatase inhibitor, which is a synthetic benzyltriazole derivative. By inhibiting aromatase, letrozole can reduce the level of estrogen, so as to eliminate the stimulating effect of estrogen on tumor growth. The in vivo activity is 150-250 times stronger than that of the first generation aromatase inhibitor amlumide. Because of its high selectivity, it does not affect the function of glucocorticoid, mineralocorticoid and thyroid. High dose use has no inhibitory effect on the secretion of adrenal corticosteroids, so it has a high therapeutic index. Preclinical studies have shown that letrozole has no potential toxicity, mutagenic and carcinogenic effects on various systems and target organs of the body, and has less toxic and side effects, good tolerance. Compared with other aromatase inhibitors and anti estrogen drugs, letrozole has stronger anti-tumor effect. It is suitable for the treatment of patients with advanced breast cancer who are not effective in the treatment of estrogen and early treatment of breast cancer.
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Mixed Tocopherols
Brief Introduction
Using mixed tocopherol concentrate as raw material, various specifications of mixed natural vitamin E are purified and compounded through chemical processes such as pretreatment, adsorption separation and molecular distillation.
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Tocopherol content: 70% - 90%
/
Food Grade
10kg
/
Plastic Drum
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2,4-Dihydroxypyrimidine; 4-Hydroxy-2(1H)-Pyrimidinone; 4-Pyrimidinol; 4-Pyrimidone; 4H-Pyrimidin-2-one; Beta-Uracil; NSC 767; Uracil-4-ol; 2,4(1H,3H)-Pyrimidinedione; 2,4-Dioxo-3,4-Dihydropyrimidin; Urasil; 1H-Pyrimidine-2,4-Dione; 2,4-Pyrimidinediol
Brief Introduction
Uracil is an organic base, one of the four main bases in RNA, a major pyrimidine component in RNA, and also a component of various uridine acids. The triphosphate compound of uridine is urine triphosphate, which is the precursor of uracil in the process of ribonucleic acid biosynthesis. Urine triphosphate as coenzyme participates in the synthesis of some sugar biochemical books.
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Chuangxin Biotech
≥99%
/
Pharm Grade
20kg
/
Fibre Drum
CAS:75607-67-9
Molecular Formula:C10H13FN5O7P
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9-Beta-D-Arabinofuranosyl-2-Fluoroadenine5’-Monophosphate; Fludarabinemonophosphate; 9-Beta-D-Arabinofuranosyl-2-Fluoroadenine-5'-Dihydrogen Phosphate; Fludarabine(NSC-118218)Phosphate; 2-Fluoro-9-(5-o-Phosphono-beta-d-Arabinofuranosyl)-9h-Purin-6-Amine; 2-Fluoro-Araamp;9-beta-Arabinofuranosyl-2-Fluoroadchemicalbookenine-5’-Phosphate; 5-Monophosphate
Brief Introduction
It has a role as an antimetabolite, an antineoplastic agent, an immunosuppressive agent, an antiviral agent, a prodrug and a DNA synthesis inhibitor.
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CAS:85622-93-1
Molecular Formula:C6H6N6O2
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Temodar; 4-Methyl-5-Oxo-2,3,4,6,8-Pentazabicyclo[4.3.0]Nona-2,7,9-Triene-9-Carboxamide; Methazolastone; 3,4-Dihydro-3-Methyl-4-Oxoimidazo[5,1-D]-1,2,3,5-Tetrazin-4(3H)-One; TMZ
Brief Introduction
Temozolomide is the first oral effective imidazo tetrazine antitumor drug. It belongs to the second generation alkylating agent with antitumor activity. It does not need intrahepatic metabolic activation after oral administration. It is characterized by easy penetration through the blood-brain barrier, good tolerance and no superimposed toxicity with other drugs. It has synergistic effect with radiotherapy. It is suitable for malignant gliomas that relapse after routine treatment, For example, glioblastoma multiforme or degenerative astrocytoma is also the first-line drug for the treatment of metastatic melanoma.
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