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CAS:107007-99-8
Molecular Formula:C18H25ClN4O
1-Methyl-N-[(3-Endo)-9-Methyl-9-Azabicyclo[3.3.1]Non-3-Yl]-1H-Indazole-3-Carboxamide; 1-Methyl-N-[(1S,5R)-9-Methyl-9-Azabicyclo[3.3.1]Nonan-3-Yl]Indazole-3-Carboxamide,Hydrochloride; 1-Methyl-N-(9-Methyl-9-Azabicyclo(3.3.1)Non-3-Yl)-1H-Indazole-3-Carboxamid; Endo-Monohydrochlorid; 1-Methylindazole-3-Carboxylic acid; Midehydrochloride; 1-Methyl-N-[(3-Endo)-9-Methyl-9-Azabicyclo[3.3.1]Non-3-Yl]-1H-Indazole-3-Carboxamide Hydrochloride; 1-Methyl-N-(9-Methyl-9-Azabicyclo[3.3.1]Nonan-3-Yl)-1H-Isoindole-3-Carboxamide Hydrochloride
Brief Introduction
Granisetron hydrochloride is a highly selective 5-HT3 receptor antagonist, which has good preventive and therapeutic effects on nausea and vomiting caused by radiotherapy, chemotherapy and surgery. Radiotherapy, chemotherapy and surgery can cause the release of 5-HT from the intestinal chromaffin cells. 5-HT can activate the 5-HT3 receptor of the central or vagus nerve and cause vomiting reflex. The mechanism of controlling nausea and vomiting is to inhibit the occurrence of nausea and vomiting by antagonizing 5-HT3 receptors in central chemosensory area and peripheral vagus nerve endings. It has high selectivity and no side effects such as extrapyramidal reaction and excessive sedation.
CAS:120511-73-1
Molecular Formula:C17H19N5
Ici-D-1033; Zd-1033; Anastrol; 1,3-Benzenediacetonitrile; Anastrazole; 2,2'-(5-((1H-1,2,4-Triazol-1-Yl)Methyl)-1,3-Phenylene)Bis(2-Methylpropanenitrile); 4-Triazol-1-Ylmethyl)-1; Anastrolozole; Anatrozole; Anastrozol; Arimidex; 1-[3,5-Di-(1-Methyl-1-Cyano)-Ethyl]-Benzyl-1,2,4-Triazole; α,α,α’,α'-Tetramethyl-5-(1H-1,2,4-Triazol-1-Ylmethyl)-1,3-Benzenediacetonitrile; 2-[3-(2-Cyanopropan-2-Yl)-5-(1,2,4-Triazol-1-Ylmethyl)Phenyl]-2-Methylpropanenitrile; α1,α1,α3,α3-Tetramethyl-5-(1H-1,2,4-Triazol-1-Ylmethyl)-1,3-Benzenediacetonitrile
Brief Introduction
Anastrozole is a potent selective three azole aromatase inhibitor, which inhibits the cytochrome P-450 dependent aromatase and thus blocks the biosynthesis of estrogen. Estrogen is a major factor in stimulating the growth of breast cancer cells. Letrozole is suitable for postmenopausal women with advanced breast cancer, and is used for second-line treatment after the failure of anti estrogen therapy.
CAS:122111-03-9
Molecular Formula:C9H12ClF2N3O4
2'-Deoxy-2',2'-Difluorocytidine; Gemcitabine Hcl(Tabines); 2’,2’-Difluorodeoxycytidinemonohydrochloride; 2’-Deoxy-2’,2’-Difluorocytidinemonohydrochloride; 2’-Deoxy-2’,2’-Difluoro-Cytidinmonohydrochloride; Gemzar; Ly188011; Ly188011 Hydrochloride; 2',2'-Difluoro-2'-Deoxycytidine
Brief Introduction
Gemcitabine hydrochloride is a synthetic new type of two fluoronucleoside antitumor drug developed by Eli Lilly. It was approved in 1995 in South Africa, Sweden, Holland, Australia and other countries. In 1996, the US Food and Drug Administration approved the first line treatment for non-small cell lung cancer and pancreatic cancer. Gemcitabine hydrochloride, a nucleoside homologue, is a cell cycle specific antitumor drug. It mainly kills cells in S phase (DNA synthesis) and blocks the transition of cell proliferation from G1 to S phase. Gemcitabine is suitable for the treatment of advanced or metastatic pancreatic cancer and locally advanced or metastatic non-small cell lung cancer, advanced and non-small cell lung cancer, pancreatic cancer, bladder cancer, breast cancer and other solid tumors.
CAS:147-94-4
Molecular Formula:C9H13N3O5
Cytosine β-D-Arabinofuranoside; 4-Amino-1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-Yl)Pyrimidin-2(1H)-One; 4-Amino-1-β-D-Arabinofuranosyl-2(1H)-Pyrimidinone; 4-Amino-1-[(2R,3S,4S,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]Pyrimidin-2-One; Cytosine β-D-Arabinofuranosid; Depocyt (Cytarabine); 4-Amino-1-[(2R,3S,4S,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-1,2-Dihydropyrimidin-2-One; 4-Amino-1-Beta-D-Arabinofuranosyl-2(1H)-Pyrimidinone; Arabinocytidine; Cytosine Beta-D-Arabinofuranoside; Ara-C; Ara-Cell
Brief Introduction
Cytarabine is a kind of purine nucleoside antiviral drug which is extracted from Streptomyces culture medium and synthesized by chemical method. It is slightly soluble in water, and its monophosphate is easily soluble in water. It can inhibit HSV1 and HSV2, hepatitis B virus, varicella zoster virus and cytomegalovirus, but has no effect on smallpox virus, adenovirus, other DNA or RNA viruses, bacteria and fungi. At present, the exact mechanism of cytosine arabinoside antiviral has not been fully elucidated, which is mainly related to the inhibition of virus replication. Drugs and their metabolites block the synthesis of viral DNA by inhibiting viral DNA polymerase, while drugs only penetrate into viral DNA molecules in a very small amount. Cytarabine is also one of the most effective drugs for the treatment of acute non lymphocytic myeloid leukemia in China.
CAS:220127-57-1
Molecular Formula:C30H35N7O4S
4-[(4-Methyl-1-Piperazinyl)Methyl]-N-[4-Methyl-3-[[4-(3-Pyridinyl)-2-Pyrimidinyl]Amino]Phenyl]-Benzamide Monomethanesulfonate; 4-[(4-Methylpiperazin-1-Yl)Methyl]-N-[4-Methyl-3-[(4-Pyridin-3-Ylpyrimidin-2-Yl)Amino]Phenyl]Benzamide Methanesulfonate
Brief Introduction
This product is an anti-tumor drug.
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