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Antineoplastic Agents

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CAS:656247-18-6
Molecular Formula:C33H39N5O7S
3-Z-[1-(4-(N-((4-Methyl-Piperazin-1-Yl)-Methylcarbonyl)-N-Methyl-Amino)-Anilino)-1-Phenyl-Methylene]-6-Methoxycarbonyl-2-Indolinone Monoethanesulphonate; Ethanesulfonic Acid - Methyl (3Z)-3-{[(4-{Methyl[(4-Methyl-1-Pipe Razinyl)Acetyl]Amino}Phenyl)Amino](Phenyl)Methylene}-2-Oxo-6-Indo Linecarboxylate (1:1); Methyl (3Z)-3-[({4-[N-Methyl-2-(4-Methylpiperazin-1-Yl)Acetamido]Phenyl}Amino)(Phenyl)Methylidene]-2-Oxo-2,3-Dihydro-1H-Indole-6-Carboxylate Ethanesulfonate Salt; 3-Z-[1-(4-(N-((4-Methyl-Piperazin-1-Yl)-Methylcarbonyl)-N-Methyl-Amino)-Anilino)-1-Phenyl-Methylene]-6-Methoxycarbonyl-2-Indolinone Monoethanesulfonate Salt; (3S,5S)-3,5-Bis[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-1-Hydroxy-Cyclohexanecarboxylic Acid Methyl Ester
Brief Introduction
Nitanib ethylsulfonate is a small molecule inhibitor of multi receptor tyrosine kinase and non receptor tyrosine kinase. In 2014, it was approved by FDA for the first time, and was developed and sold by bringer Ingelheim company for the first time. It has been approved by the US Food and Drug Administration (FDA), the European Drug Administration (EMA) and the agency for drugs and medical devices (PMDA) for the treatment of idiopathic pulmonary fibrosis, and by EMA for non-small cell lung cancer.
CAS:66-22-8
Molecular Formula:C4H4N2O2
2,4-Dihydroxypyrimidine; 4-Hydroxy-2(1H)-Pyrimidinone; 4-Pyrimidinol; 4-Pyrimidone; 4H-Pyrimidin-2-one; Beta-Uracil; NSC 767; Uracil-4-ol; 2,4(1H,3H)-Pyrimidinedione; 2,4-Dioxo-3,4-Dihydropyrimidin; Urasil; 1H-Pyrimidine-2,4-Dione; 2,4-Pyrimidinediol
Brief Introduction
Uracil is an organic base, one of the four main bases in RNA, a major pyrimidine component in RNA, and also a component of various uridine acids. The triphosphate compound of uridine is urine triphosphate, which is the precursor of uracil in the process of ribonucleic acid biosynthesis. Urine triphosphate as coenzyme participates in the synthesis of some sugar biochemical books.
CAS:75607-67-9
Molecular Formula:C10H13FN5O7P
9-Beta-D-Arabinofuranosyl-2-Fluoroadenine5’-Monophosphate; Fludarabinemonophosphate; 9-Beta-D-Arabinofuranosyl-2-Fluoroadenine-5'-Dihydrogen Phosphate; Fludarabine(NSC-118218)Phosphate; 2-Fluoro-9-(5-o-Phosphono-beta-d-Arabinofuranosyl)-9h-Purin-6-Amine; 2-Fluoro-Araamp;9-beta-Arabinofuranosyl-2-Fluoroadchemicalbookenine-5’-Phosphate; 5-Monophosphate
Brief Introduction
It has a role as an antimetabolite, an antineoplastic agent, an immunosuppressive agent, an antiviral agent, a prodrug and a DNA synthesis inhibitor.
CAS:85622-93-1
Molecular Formula:C6H6N6O2
Temodar; 4-Methyl-5-Oxo-2,3,4,6,8-Pentazabicyclo[4.3.0]Nona-2,7,9-Triene-9-Carboxamide; Methazolastone; 3,4-Dihydro-3-Methyl-4-Oxoimidazo[5,1-D]-1,2,3,5-Tetrazin-4(3H)-One; TMZ
Brief Introduction
Temozolomide is the first oral effective imidazo tetrazine antitumor drug. It belongs to the second generation alkylating agent with antitumor activity. It does not need intrahepatic metabolic activation after oral administration. It is characterized by easy penetration through the blood-brain barrier, good tolerance and no superimposed toxicity with other drugs. It has synergistic effect with radiotherapy. It is suitable for malignant gliomas that relapse after routine treatment, For example, glioblastoma multiforme or degenerative astrocytoma is also the first-line drug for the treatment of metastatic melanoma.
CAS:10212-25-6
Molecular Formula:C9H12ClN3O4
2,2'-Anhydro-(1-β-D-Arabinofuranosyl)Cytosine Hydrochloride; 2,2'-Anhydro-1-Beta-D-Arabinofuranosylcytosine Hydrochloride; 1-Beta-D-Arabinofuranosyl-2,2'-Anhydro-Cytosinhydrochloride; Cyclocytidine HCL , Cytidine; O-2,2'-Cyclocytidinemonohydrochloride; (2R,4R,5R,6S)-4-(Hydroxymethyl)-10-Imino-3,7-Dioxa-1,9-Diazatricyclo[6.4.0.02,6]Dodeca-8,11-dien-5-ol;Hydrochloride
Brief Introduction
Ancitabine Hydrochloride is effective for all types of acute leukemia and meningeal leukemia.
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